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Data acquisition modes for LC–MS-based untargeted metabolomics
In this interview we caught up with Jian Guo (University of British Columbia, Vancouver, Canada) to discuss his presentation at ASMS 2020 Reboot. Jian discusses his research inspirations, current...
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Metabolomics: an evolving field
Metabolomics is one of the ‘-omics’ sciences. Of the ‘-omics’ sciences – genomics, transcriptomics, proteomics and metabolomics – it is the only -omics science which directly reflects the underlying...
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Biomarkers identified for screening and potentially treating patients with...
Researchers from the Lawson Health Research Institute, Western University (both ON, Canada) and the University of Alberta (AB, Canada) have identified three metabolites in the blood that appear to be...
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Pillararene molecule can be used as biosensor to detect low-molecular-weight...
A study conducted by researchers at Kanazawa University (Japan) reports on a molecule known as pillar[6]arene (P6A) that can form a host–guest compound with a cancer-associated metabolite, which can...
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Thorough characterization of difficult-to-classify metabolites enabled by...
This webinar will introduce why thorough characterization of drug candidate metabolism is a requisite part of early- to late-stage drug discovery. Early ADME studies are used to determine if a drug...
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Quantitative analysis and metabolite profiling of oligonucleotides
INTRODUCTION In this presentation, Liam Moran of Charles River Laboratories (OH, USA) discusses the current state, challenges and the future of oligonucleotide development and analysis. Therapies...
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Review on in vivo profiling of drug metabolites with LC-MS/MS in the past decade
Reddy GN, Laltanpuii C, Sonti R | Bioanalysis, 13(22), 1697–1722 (2021) Keywords: biotransformation • LC–MS • metabolite profiling • plasma • urine Metabolite profiling is an indispensable part of...
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Metabolic biomarkers in urine demonstrate quality of diet in European children
A large metabolic study of over 1000 children provides further evidence for the benefits of the Mediterranean diet and proposes urinary analysis as a method of assessing metabolic health and diet...
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New system of meningioma classification better predicts disease prognosis
One-fifth of meningiomas that are classified as ‘benign’ utilizing standard clinical analysis eventually demonstrate malignant behavior. In a new study, researchers suggested that multiple reported...
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Metabolic profiling in the arena of gut–brain interaction studies for...
O Deda & H G Gika | Bioanalysis, 12(8), 501-504 (2020) Keywords: • Alzheimer’s disease • gut–brain interaction • metabolic profiling • metabolites Since 400 BC, Hippocrates theorized that ‘bad...
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Could consuming vinegar every day ease depression?
A study investigating daily vinegar consumption in overweight but healthy adults has demonstrated that 4 weeks of vinegar intake led to notable improvements in self-reported depression scores. A shot...
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A 2-in-1 discovery for diagnosing and treating endometriosis
Researchers at Baylor College of Medicine (TX, USA), along with collaborators from the University of Arizona (AZ, USA) and Washington University (MO, USA), have shared some promising discoveries that...
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